Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1995 1
1996 5
1997 1
1998 1
1999 3
2000 4
2001 3
2002 7
2003 6
2004 13
2005 7
2006 14
2007 6
2008 6
2009 9
2010 10
2011 8
2012 11
2013 14
2014 9
2015 14
2016 16
2017 8
2018 8
2019 11
2020 6
2021 6
2022 8
2023 7
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

201 results

Results by year

Filters applied: . Clear all
Page 1
Therapeutic roles of curcumin: lessons learned from clinical trials.
Gupta SC, Patchva S, Aggarwal BB. Gupta SC, et al. AAPS J. 2013 Jan;15(1):195-218. doi: 10.1208/s12248-012-9432-8. Epub 2012 Nov 10. AAPS J. 2013. PMID: 23143785 Free PMC article. Review.
Some promising effects have been observed in patients with various pro-inflammatory diseases including cancer, cardiovascular disease, arthritis, uveitis, ulcerative proctitis, Crohn's disease, ulcerative colitis, irritable bowel disease, tropical pancreatitis, peptic ulcer, gast …
Some promising effects have been observed in patients with various pro-inflammatory diseases including cancer, cardiovascular disease, arthr …
LOX-1 and cancer: an indissoluble liaison.
Murdocca M, De Masi C, Pucci S, Mango R, Novelli G, Di Natale C, Sangiuolo F. Murdocca M, et al. Cancer Gene Ther. 2021 Nov;28(10-11):1088-1098. doi: 10.1038/s41417-020-00279-0. Epub 2021 Jan 5. Cancer Gene Ther. 2021. PMID: 33402733 Free PMC article. Review.
In recent years, LOX-1 upregulation in different tumors evidenced its involvement in cancer onset, progression and metastasis. In this review, we outline the role of LOX-1 in tumor spreading and metastasis, evidencing its function in VEGF induction, HIF-1alpha activ …
In recent years, LOX-1 upregulation in different tumors evidenced its involvement in cancer onset, progression and metastasis. In thi …
LOX-1 receptor: A potential link in atherosclerosis and cancer.
Balzan S, Lubrano V. Balzan S, et al. Life Sci. 2018 Apr 1;198:79-86. doi: 10.1016/j.lfs.2018.02.024. Epub 2018 Feb 17. Life Sci. 2018. PMID: 29462603 Review.
Several different types of cancer reported LOX-1 gene upregulation, and numerous interplays exist concerning LOX-1 in atherosclerosis, metabolic diseases and cancer. ...The remodeling proteins MMP-2 and MMP-9 have been found increased in angiogenesis in atherosclero …
Several different types of cancer reported LOX-1 gene upregulation, and numerous interplays exist concerning LOX-1 in atherosc …
Downregulation of LOX promotes castration-resistant prostate cancer progression via IGFBP3.
Chen X, Shao Y, Wei W, Shen H, Li Y, Chen Y, Ma Q, Li H, Yang Z, Niu Y, Shang Z. Chen X, et al. J Cancer. 2021 Oct 28;12(24):7349-7357. doi: 10.7150/jca.61131. eCollection 2021. J Cancer. 2021. PMID: 35003355 Free PMC article.
The role of lysyl oxidase (LOX) in prostate cancer remains controversial. Studies have shown that LOX may inhibit the progression of prostate cancer (PCa), whereas other studies demonstrate that LOX may act as a tumor activator in PCa. ...We sho …
The role of lysyl oxidase (LOX) in prostate cancer remains controversial. Studies have shown that LOX may inhibit the p …
LOX-1 Activation by oxLDL Induces AR and AR-V7 Expression via NF-kappaB and STAT3 Signaling Pathways Reducing Enzalutamide Cytotoxic Effects.
Duprat F, Robles C, Castillo MP, Rivas Y, Mondaca M, Jara N, Roa F, Bertinat R, Toledo J, Paz C, González-Chavarría I. Duprat F, et al. Int J Mol Sci. 2023 Mar 7;24(6):5082. doi: 10.3390/ijms24065082. Int J Mol Sci. 2023. PMID: 36982155 Free PMC article.
Furthermore, LOX-1/oxLDL function has been associated with other diseases, such as obesity, hypertension, and cancer. In prostate cancer (CaP), LOX-1 overexpression is associated with advanced stages, and its activation by oxLDL induces an epithelial-mesenchy …
Furthermore, LOX-1/oxLDL function has been associated with other diseases, such as obesity, hypertension, and cancer. In prostate …
LOX-1 activation by oxLDL triggers an epithelial mesenchymal transition and promotes tumorigenic potential in prostate cancer cells.
González-Chavarría I, Fernandez E, Gutierrez N, González-Horta EE, Sandoval F, Cifuentes P, Castillo C, Cerro R, Sanchez O, Toledo JR. González-Chavarría I, et al. Cancer Lett. 2018 Feb 1;414:34-43. doi: 10.1016/j.canlet.2017.10.035. Epub 2017 Nov 14. Cancer Lett. 2018. PMID: 29107109
Furthermore, high levels of oxLDL, the main ligand for LOX-1, have been found in patients with advanced prostate cancer. However, the role of LOX-1 in prostate cancer has not been unraveled completely yet. ...
Furthermore, high levels of oxLDL, the main ligand for LOX-1, have been found in patients with advanced prostate cancer. Howev …
Radiotherapy Increases 12-LOX and CCL5 Levels in Esophageal Cancer Cells and Promotes Cancer Metastasis via THP-1-Derived Macrophages.
Mi S, Qu Y, Chen X, Wen Z, Chen P, Cheng Y. Mi S, et al. Onco Targets Ther. 2020 Aug 5;13:7719-7733. doi: 10.2147/OTT.S257852. eCollection 2020. Onco Targets Ther. 2020. PMID: 32801779 Free PMC article.
BACKGROUND: Dioxygenase 12-lipoxygenase (12-LOX) plays an important role in tumorigenesis and promotes angiogenesis and proliferation in several tumors, including prostate and breast tumors. ...CCL5 expression was increased by 12-LOX upregulation but was supp …
BACKGROUND: Dioxygenase 12-lipoxygenase (12-LOX) plays an important role in tumorigenesis and promotes angiogenesis and proliferation …
Arachidonate 15-lipoxygenase type B: Regulation, function, and its role in pathophysiology.
Benatzy Y, Palmer MA, Brüne B. Benatzy Y, et al. Front Pharmacol. 2022 Nov 9;13:1042420. doi: 10.3389/fphar.2022.1042420. eCollection 2022. Front Pharmacol. 2022. PMID: 36438817 Free PMC article. Review.
As a lipoxygenase (LOX), arachidonate 15-lipoxygenase type B (ALOX15B) peroxidizes polyenoic fatty acids (PUFAs) including arachidonic acid (AA), eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and linoleic acid (LA) to their corresponding fatty acid hydroperoxide …
As a lipoxygenase (LOX), arachidonate 15-lipoxygenase type B (ALOX15B) peroxidizes polyenoic fatty acids (PUFAs) including arachidoni …
PTEN loss and activation of K-RAS and beta-catenin cooperate to accelerate prostate tumourigenesis.
Jefferies MT, Cox AC, Shorning BY, Meniel V, Griffiths D, Kynaston HG, Smalley MJ, Clarke AR. Jefferies MT, et al. J Pathol. 2017 Dec;243(4):442-456. doi: 10.1002/path.4977. Epub 2017 Nov 14. J Pathol. 2017. PMID: 29134654 Free PMC article.
Aberrant phosphoinositide 3-kinase (PI3K), mitogen-activated protein kinase (MAPK) and WNT signalling are emerging as key events in the multistep nature of prostate tumourigenesis and progression. Here, we report a compound prostate cancer murine model in which thes …
Aberrant phosphoinositide 3-kinase (PI3K), mitogen-activated protein kinase (MAPK) and WNT signalling are emerging as key events in the mult …
201 results